How to Farm Mythic Uniques (Season 6)

Introduction

Mythic Uniques are the rarest and most powerful items in Diablo 4. They have unique effects that can drastically change your build and gameplay. However, Mythic Uniques are extremely hard to find and only have around a 2% chance to drop from farming endgame or certain bosses. Two of these bosses are Uber Duriel, and Uber Andariel, who have a higher chance of dropping Mythic Uniques than any other boss in the game.

Uber Bosses are some of the most challenging but rewarding bosses in Diablo 4. To fight them, you need to reach a decent level and access Torment difficulty. Additionally, you also have to collect the necessary materials in order to summon Uber versions of Duriel or Andariel in their dungeon lair. Once all the requirements are met, you can farm these bosses for a chance of getting one or more Mythic Uniques.

Requirements and Preparation

If you want to obtain Mythic Uniques through killing bosses, keep in mind that they have a higher chance of dropping from Uber Duriel, King of Maggots, and Andariel, the Maiden of Anguish. However, Uber bosses can not be summoned in any World Tier lower than Torment difficulty. To summon them, you will need to farm the following materials.

To summon Uber Duriel:

• 2 Mucus-Slick Egg (drop from Varshan)
• 2 Shard of Agony (drop from Grigoire, The Galvanic Saint)

To summon Uber Andariel:

• 2 Sandscorched Shackles (drop from Lord Zir)
• 2 Pincushioned Doll (drop from the Beast in the Ice)

Mucus Slick Eggs: Varshan

Mucus-Slick Eggs drop from The Echo of Varshan. Varshan can be summoned inside the Malignant Burrow, right next to the Tree of Whispers. You will need 4 Malignant Heart in order to summon Varshan.

The Malignant Heart can drop from Whisper Caches. To receive a Whisper Cache, simply complete 10 Whispers of the Dead objectives and then head back to the Tree of Whispers. Again, we would recommend farming Whispers within active Helltide zones, for extra efficiency.

Shards of Agony: Grigoire

Shard of Agony drop from Grigoire, The Galvanic Saint. Grigoire can be summoned inside the Hall of the Penitent, south of Ked Bardu. You will need the following materials in order to summon Grigoire:

• 12 Living Steel

Living Steel can only be obtained during Helltide events, by opening Tortured Gifts of Living Steel Chests. Those chests are similar to Helltide Mystery Chests. They cost 275 Cinders to open, and are located in specific zones inside Helltide. Only two chests are active at the same time. In order to know the locations they can spawn, you can check our Living Steel chest locations guide.

If you can, try to participate in any Helltide event you encounter, and focus on farming 275+ Cinders in order to open at least one Tortured Gift of Living Steel per Helltide.

Furthermore, if you can team up with other players, we highly recommend it, as any of these materials can be traded, and only one player inside the party needs to possess all of them in order to summon the bosses. This way, you can exchange the needed materials and target-farm the bosses to collect as many items as possible for Uber Duriel or Uber Andariel. Make sure to farm for more than one, this way you maximize your farming time by facing the bosses multiple times in a row.

Sandscorched Shackles: Lord Zir

Sandscorched Shackles drop from Lord Zir. To summon him, acquire 12x Exquisite Blood from World Bosses or Legion Events. Then, travel to the Darkened Way near Kyovashad, where you will find Lord Zir.

Pincushioned Dolls: Beast in the Ice

Pincushioned Doll drop from The Beast in the Ice. To summon him, acquire 12x Distilled Fear from Nightmare Dungeons, Whisper Cache or local events. Then, travel to the Glacial Fissure Dungeon, where you will find The Beast in the Ice.

Summoning Uber Duriel

Once you have farmed enough Mucus-Slick Egg and Shard of Agony, head to the south of Kehjistan, next to Gea Kul, and travel to the Gaping Crevasse dungeon.

Inside, head to the Altar. If you are in a party, only one player will have to interact with the Altar in order to use the materials. This will then summon Uber Duriel, and the fight will begin!

If you wish to know more details about Uber Duriel’s mechanics and how to defeat him, take a look at our guide below.

Summoning Uber Andariel

Andariel is another boss that will have the same Mythic Unique drop pool as Duriel. To face Andariel, players must venture to the Hanged Man’s Hall in Kehjistan, located near Tarsarak. The summoning ritual involves specific parts that can be obtained from the Beast in the Ice and Lord Zir.

Uber Andariel requires the following items:

• 2 Sandscorched Shackles (drop from Lord Zir)
• 2 Pincushioned Doll (drop from the Beast in the Ice)

For more details about Uber Andariel’s mechanics and how to defeat her, check out our guide below.

Mythic Uniques

Once Uber Duriel is defeated, you will have a higher chance of getting one of the following Mythic Uniques as a reward:

• Ahavarion, Spear of Lycander (Druid, Sorcerer)
• Doombringer (Barbarian, Necromancer, Rogue)
• The Grandfather (Barbarian, Necromancer)
• Nesēkēm, the Herald (Spiritborn)
• Harlequin Crest (All Classes)
• Andariel’s Visage (All Classes)
• Tyrael’s Might (All Classes)
• Ring of Starless Skies (All Classes)
• Melted Heart of Selig (All Classes)

Furthermore, Lord Zir and the Beast in the Ice have a small chance of dropping Mythic Uniques.

Crafting Mythic Uniques

Through the use of Resplendent Spark, players can craft a Mythic Unique they want. Here is how it works:

After you have spent some time target farming Uber Duriel or Uber Andariel, and collected a number of unwanted or duplicate Mythic Uniques, you can salvage them to obtain a new material called Resplendent Spark, which can be used to create the Mythic Unique you want.

When salvaging any Mythic Unique, you will get 1 Resplendent Spark. Once you have collected 2 of those sparks, head to the Blacksmith and craft a Mythic Unique Cache with 2 Resplendent Spark to create a random Mythic Unique.

With Vessel of Hatred, the Jeweler Rune Crafting tab offers the option to craft Mythic Uniques in exchange for 2 Resplendent Spark and 3x 6 different Legendary Runes.

In addition, the chances of dropping Mythic Uniques have increased. If you are bored of farming Uber Bosses, other methods (Whisper Caches, Nightmare Dungeons, etc.) are now more likely to drop Mythic Uniques. Good luck!

Summary

Mythic Uniques are very powerful items that can drastically alter a build or playstyle. They can be extremely challenging to find, but through target farming or killing Uber Duriel and Uber Andariel, players have a higher chance of getting their hands on one of them!

Make sure to team up with other players in order to maximize your farming time and materials obtained. Moreover, don’t hesitate to trade with each other to make sure you can farm Uber Duriel or Uber Andariel multiple times in a row. May the loot be in your favor!